Journey

Respond to a medicines or controlled drugs incident

What to do when a medicines incident occurs: medication error, controlled drug discrepancy, or CD theft/loss. Covers securing the patient and evidence, internal reporting, statutory notifications to CQC, MHRA Yellow Card, police notification for CD theft, investigation, Accountable Officer responsibilities, and corrective actions.

Healthcare & Social Care Running a Business Updated 15 September 2026
5 milestones references 3 guides

If a medicines incident has occurred - a medication error, a controlled drug discrepancy, or suspected theft or loss of controlled drugs - this guide helps you respond correctly. Patient safety comes first, followed by evidence preservation, internal reporting, and statutory notifications.

  1. Secure the patient and the scene

  2. Report internally

  3. Make statutory notifications

    Medicines and controlled drugs compliance

    Controlled drug register requirements, Accountable Officer duties, standard operating procedures for CD management, and statutory notification obligations for CD incidents.

  4. Investigate the incident

    Clinical governance and quality frameworks

    Governance structures for incident investigation, learning from events, clinical audit, and CQC well-led requirements for healthcare providers.

  5. Implement corrective actions

    Medical devices compliance

    If a medical device was involved in the incident, review your obligations for adverse incident reporting, device maintenance, and MHRA notifications.